If you are looking for a College Football Week 12 betting preview with picks and predictions for the Penn State vs Michigan State matchup, we have you covered! Our college football handicapping experts discuss this matchup from a sports betting perspective, sharing their picks and predictions vs. the current odds.
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Penn State vs Michigan State Betting Preview College Football Week 12
📍 Game Details
Date: Saturday, November 15, 2025
Kick-off: 3:30 p.m. ET / 2:30 p.m. CT at Spartan Stadium — East Lansing, Michigan.
How to Watch: Nationally on CBS.
📊 Betting Info
Spread: Penn State favored by approximately -7 points.
Total (Over/Under): Around 49.5 points.
🏈 Interesting Facts & Storylines
Team hashtags you can use: #WeArePennState for Penn State; #GoGreen for Michigan State.
Rivalry & Trophy: The Penn State–Michigan State rivalry is known as “The Battle for the Land Grant Trophy.” Penn State leads the series 19–18–1.
Trend: Both teams have hit the “Over” on the total six times this season in their games, and both four times in Big Ten play.
Matchup context: Penn State enters this game with focus on its offense moving forward, while Michigan State is defending home turf at Spartan Stadium.
🔖 Hashtags & Social
#WeArePennState #GoGreen #BigTen #CollegeFootball #CFB #PennState #MichiganState
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